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Mechanobiology and Nano-robots in Biomedicines

Seminar /

Seminar Mechanobiology and Nano-robots in Biomedicines On July 24, 2023, Associate Professor Do Duc Ton, School of Engineering and Digital Sciences, and Assistant Professor Pham Thanh Tri, School of Sciences and Humanities, from Nazarbayev University visited International University, VNU-HCMC and delivered an interesting seminar on Mechanobiology And Nanorobot In Biomedicines. Asst. Prof. Pham Thanh Tri demonstrated the use of atomic force microscopy (AFM) combined with live-cell imaging in investigating the mechanics of asymmetric cell division (ACD). He also shared his current projects studying the effect of nanoparticles on bacteria, plant, and mammalian cells and the application of magnetic nanoparticles (MNP) in research and medicines.  Assoc. Prof. Do Duc Ton expanded on the topic of nano-robots in biomedicines, including using functionalized magnetic fields to guide MNP across the Blood-Brain Barrier and the developnMagnetic Particle Imaging. The seminar took place successfully with the participation of researchers and students, piquing their interest in the field of mechanobiology and nanorobots. The seminar also opened many collaboration opportunities, on modeling bacterial growth under the effect of nanoparticles.

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[Keynote Speaker] Michael Otto, Ph.D

Other /

Michael Otto, Ph.D Biography   Dr. Otto received his M.S. in biochemistry in 1993 from the University of Tübingen, Germany. In 1998, he earned his Ph.D. in microbiology from the same institution. Dr. Otto joined the Laboratory of Human Bacterial Pathogenesis in July 2001 as a principal investigator. In 2008, he became a tenured senior investigator and moved his laboratory to the NIH Bethesda main campus. He is currently chief of the Pathogen Molecular Genetics Section in the Laboratory of Bacteriology at NIAID.  He has published more than 200 papers in reputed journals and has been serving as an editorial advisory board member of PLoS Pathogens, Infection and Immunity, and the Journal of Bacteriology, among others. Major Areas of Research Staphylococcal infection and colonization Bacterial interactions with the host and the host microbiota Antibiotic resistance in Staphylococcus aureus (MRSA) Biofilm development and infection

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[Keynote Speaker] Zhou Yiting, Ph.D

Other /

Zhou Yiting, Ph.D Biography  Dr, Zhou Yiting is Professor and Assistant Dean at School of Medicine, Zhejiang University.  His research interest includes Myogenesis and tenogenesis. Differentiation of skeletal muscle progenitors into multinucleated myotubes is a multi-step process that undergoes dramatic morphological changes and genetic reprogramming. The main focus of his lab is to elucidate molecular mechanisms for spatialtemporal regulation of myoblast differentiation and muscle regeneration. In addition, we are also interested in signaling pathways controlling insulin/IGF signaling. Current effort is geared towards (1) identifying the roles of phase separation in modulating insulin/IGF pathway and (2) delineating the roles of metabolic reprogramming in regulating cell fate decision.  

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[Keynote Speaker] Nguyen Viet Tuan, Ph.D

Other /

Nguyen Viet Tuan, Ph.D Biography  Dr. Nguyen Viet Tuan finished his Master of Applied Science at QUT, Brisbane and his PhD at University of the Sunshine Coast with multiple transcriptomics projects in aquaculture (fish/crustaceans). He is currently employed as a Research Scientist in Computational Biology at Agriculture Victoria Research, based in AgriBio building, Melbourne. His primary task at the moment is to assist with the analyses of genotyping data and sequencing data to further advance Australia dairy cows industry. His interests lies the application of Next Generation Sequencing (NGS) in agriculture species (mostly non-model species including prawns, fish.., and up to date, dairy cows), investigating gene expression profiles on different external conditions, physiological and sexual orientation of organism… He is also very interested in Long read sequencing platforms and single cell RNA-seq. His ResearchGate account can be found at https://www.researchgate.net/profile/Tuan_Nguyen33

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[Keynote Speaker] Vinod Scaria, MD

Other /

Vinod Scaria, MD Biography  Vinod Scaria is a clinician and computational biologist. His laboratory is interested in understanding the function, organization and regulation of vertebrate genome, and how genomic variations could potentially impact them. He is also involved in creating novel methods and resources for analysis and annotation of genomes and understanding the functional impact of genomic variations. He has been part of pioneering collaborative genomics projects aimed at understanding the South Asian and Middle Eastern genome diversity. He has been part of the whole genome sequencing and analysis projects including the Indian, Sri-Lankan and Malaysian genome projects and is a member of the HUGO Pan-Asian Population Genomics Initiative (HUGO-PAPGI) task-force. He is also the co-founder of the Genomics for Understanding Rare Disease: India Alliance Network (GUaRDIAN), which is the pioneer and one of the largest networks of clinicians and researchers in India working on rare genetic diseases. He has adopted novel and creative strategies, such as the use of artificial intelligence, social media, and the participation of a large number of undergraduate students in collaborative genomics projects. His research interests are:  Genomics of Rare Genetic Diseases Computational Biology on non-coding Functional RNAs Pharmacogenomics of global populations  

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[Keynote Speaker] Jaime Martinez-Urtaza, Ph.D

Other /

Jaime Martinez-Urtaza, Ph.D Biography  Dr Jaime Martinez-Urtaza is Distinguished Beatriz-Galindo Senior Professor in the Department of Genetics and Microbiology, UAB. He has previously worked at the University of Santiago de Compostela, the European Centre for Disease Control (ECDC), the University of Bath and CEFAS in the UK. He is an honorary professor at the University of Exeter (UK) and a visiting professor at the University of Southampton (UK), the University of the Frontier (Chile) and the Center for Food Research and Development-CIAD (Mexico). He is also a scientific advisor to the National Institutes of Health of Peru and an expert on FAO and WHO for water and foodborne diseases. His work covers different aspects of molecular epidemiology and the effects of climate on infectious diseases with a particular interest in the study of water and foodborne diseases. A central theme in his research is the fusion of different scientific disciplines such as molecular biology, microbiology, population genetics, oceanography, climate science and epidemiology, to decipher the occurrence and transmission of infectious diseases. In recent years, he has devoted much of his activity to the application of advanced genomic tools to identify new aspects in the evolution, transmission and dispersal of human pathogens in connection with natural events or activities associated with the activity human.

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Research Center for Infectious Diseases welcoming an international student to RCID for a summer internship.

Internship /

Research Center for Infectious Diseases welcoming an international student to RCID for a summer internship. On Monday, Jun 29, Assoc. Prof. Nguyễn Thị Thu Hoài – vice director of the Research Center for Infectious Diseases – welcomed Gregory Hunter, a Public Health and Equity Studies student from Saint Michaels College, for a summer internship. Greg connected with RCID through Abroader and will have a summer internship with the center for 2 months. Greg will be assigned to work with the Medical Microbiology group to characterize S. aureus colonization in wild boar. He will also participate in ongoing projects in the microbiology lab, which includes performing laboratory experiments and writing scientific manuscripts. RCID will host two international students this summer from Abroader.

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Research Center for Infectious Diseases and the School of Medicine – Vietnam National University, Ho Chi Minh City had a co-operation meeting on Pharmaceutical Researches

Meetings & Collaborations /

Research Center for Infectious Diseases and the School of Medicine – Vietnam National University, Ho Chi Minh City had a co-operation meeting on Pharmaceutical Researches In the morning of May 9, 2023, Assoc.Prof.Dr. Nguyen Phuong Thao – Director of Research Center for Infectious Diseases had a meeting and exchange with Prof.Dr. Le Minh Tri – Vice Dean of Faculty of Medicine – Vietnam National University, Ho Chi Minh City and other staff members: Dr. Vo Thanh Hoa – Head of the Department of Medicinal Plants – Plants, Dr. Nguyen Phuoc Vinh – Head of the Department of Apothecary – Pharmaceutical Industry. During the meeting, the center and school discussed respective research topics and potential areas of collaboration. The School of Medicine is divided into many subjects with separate areas of expertise, including Medicinal Materials – Plants and Apothecary – Pharmaceutical Industry. The two sides discussed opportunities for cooperation in research and preparation of health support products.   This exchange has laid the basis for future cooperation in research topics between the two sides. Besides Pharmaceuticals, the center and school will also have other discussions in other  aspects such as diagnostic testing, vaccine development, biomedical techniques to support medical treatment, etc.

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[CV] Tran Doan Hong Ngoc, BSc.

Full CV /

Tran Doan Hong Ngoc, BSc. Technician  Profile Publications Research Interest(s) Molecular Diagnostics Infectious Diseases Development of Poin-of-care Devices Education 2017-2022: BSc. in Biotechnology, International University, Vietnam National University in HCMC Awards 2017-2021: Undergraduate Entrance Scholarships, by International University, Vietnam National University in HCMC Featured Publications Tran, N.D., Nguyen, U.N., Thao, N.P. et al. Development of a Lateral Flow Immunoassay with Silver Enhancement for Detecting Staphylococcus aureus α-hemolysin. Appl Biochem Microbiol 60, 146–154 (2024). https://doi.org/10.1134/S0003683824010186 Publications Tran, N.D., Nguyen, U.N., Thao, N.P. et al. Development of a Lateral Flow Immunoassay with Silver Enhancement for Detecting Staphylococcus aureus α-hemolysin. Appl Biochem Microbiol 60, 146–154 (2024). https://doi.org/10.1134/S0003683824010186 Le, N. T., Do, T. T. H., Duong, D. M. T., Tran, D. H. N., Huynh, T. Q., Huynh, K., Nguyen, P. T., Le, M. T., & Nguyen, T. T. H. (2024). A machine learning approach utilizing DNA methylation as a classifier for Pulmonary Tuberculosis screening. Gene Reports, 36, 101939. https://doi.org/10.1016/j.genrep.2024.101939 Minh Hieu Vu, Doan Hong Ngoc Tran, Minh-Anh Dang-Trinh, & Huynh Chan Khon. (2024). Development of a lateral flow immunoassay with HRP enhancement for spiked SARS-CoV-2 protein N detection in human saliva. Vietnam Journal of Science, Technology and Engineering, 66(1), 111-119. https://doi.org/10.31276/VJSTE.66(1).111-119 Tien Luong, An Van, Doan Hong Ngoc Tran, Dang Phu-Hai Nguyen, Thanh-Qua Nguyen, Le-Giang Tran, Khon Huynh. Design of a printer–based line dispenser for lateral flow assay fabrication. 9th International Conference on the Development of Biomedical Engineering in Vietnam. 2022, Ho Chi Minh City, Vietnam.

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[CV] Hoang Thi Lan Xuan, MSc.

Full CV /

Hoang Thi Lan Xuan, MSc.. Collaborating PI Research Interest(s) Disease resistance response mechanism Genomics Biosignal transduction Education 2000-2006: BSc., The  University  of Queensland, Australia 2011-2012: MSc., The  University  of Queensland, Australia Publications Books and Book Chapters Xuan HTL, Nhi NHY, Thao NP, Tran L- SP (2020) NAC transcription factors in drought and salinity tolerance. In “Salt and Drought Stress Tolerance in Plants” (eds M Hasanuzzman, M Tanveer), Springer, Switzerland, pp. 351-366. Chuong NN, Nghia DHT, Le TVA, Tran L-SP, Hoang XLT, Thao NP (2020) Type 2C Protein Phosphatases in Plant Signaling Pathways under Abiotic Stress. In: Pandey G.K. (eds) Protein Phosphatases and Stress Management in Plants. Springer, Switzerland, pp 67-82. International original publication Hoang XLT, Prerostova S, Thu NBA, Thao NP, Vankova R, Tran LP (2021) Histidine Kinases: Diverse Functions in Plant Development and Responses to Environmental Conditions. Annual Review Plant Biology 72:297-323. Hoang XLT, Chuong NN, Hoa TTK, Doan H, Van PHP, Trang LDM, Huyen PNT, Le DT, Tran L-SP, Thao NP (2021). The Drought-Mediated Soybean GmNAC085 Functions as a Positive Regulator of Plant Response to Salinity. International Journal of Molecular. Sciences  22:8986. Chuong NN, Hoang XLT, Nghia DHT, Nguyen NC, Thao DTT, Tran TB, Ngoc TTM, Thu NBA, Nguyen QT, Thao NP (2021). Ectopic Expression of GmHP08 Enhances Resistance of Transgenic Arabidopsis Toward Drought Stress. Plant Cell Reports 40(5):819-834. Chuong NN, Hoang XLT, Nghia DHT, Dai TNT, Thi VL, Thao N.P. (2021) Protein Phosphatase Type 2C Functions in Phytohormone-Dependent Pathways and in Plant Responses to Abiotic Stresses. Current Protein & Peptide Science doi: 10.2174/1389203722666210322144442 Hai NN, Chuong NN, Tu NHC, Kisiala A, Hoang XLT*, Thao NP* (2020). Role and Regulation of Cytokinins in Plant Response to Drought Stress. Plants 9(4):422 (*: co- corresponding authors) Nghia DHT, Chuong NN, Hoang XLT, Nguyen NC, Tu NHC, Huy NVG, Ha BTT, Nam TNH, Thu NBA, Tran LSP, Thao NP (2020)     Heterologous     Expression     of     a      Soybean Gene RR34 Conferred Improved Drought Resistance of Transgenic Arabidopsis. Plants 9:494. Hoang XLT, Nguyen NC, Nguyen YH, Watanabe Y, Tran LP, Thao NP (2019) The Soybean GmNAC019 Transcription Factor Mediates Drought Tolerance in Arabidopsis in an Abscisic Acid- Dependent Manner. International Journal of Molecular Sciences 21(1):286. Nguyen NC, Hoang XLT, Nguyen QT, Binh NX, Watanabe Y, Thao NP, Tran LP (2019). Ectopic Expression of Glycine maxGmNAC109 Enhances Drought Tolerance and ABA Sensitivity in Arabidopsis. Biomolecules. 9(11):714. Domestic original publications Hoang XLT*, Thao NP (2021) Important Analyzing Parameters in the Assessment of Salt Tolerance in Plants. Tạp chí Công nghệ Sinh học 19(2). Published online. (*: tác giả liên hệ) Nguyen LNP, Hoang XLT, Thao NP (2021) Preliminary Examination of Anti-microbiall, Anti-oxidant and Anticancer Activities of Cordyceps militaris Cultivated in VietNam. Tạp chí Công nghệ Sinh học 17(2): 303-308. Pham NTH, Hoang XLT, Nguyen NC, Thao NP (2021) Expression Study of Stress-Related Genes in Salinity-Treated transgenic Arabidopsis Harboring Soybean Response Regulator 34. Tạp chí Công nghệ Sinh học (nhận đăng). Thai CH, Hoang XLT, Nguyen QT, Thao NP (2021) Expression Alteration Analyses in the Transgenic Arabidopsis Carrying Soybean Histidine-Containing Phosphotransmitter Gene under Salinity Stress Condition. Tạp chí Công nghệ Sinh học (nhận đăng). Tran QP, Hoang XLT, Tran AM, Nguyen TT, Thao NP, Nguyen QT (2021) Effect of Calcium Hypochlorite on Surface Strerilization and Seedling Growth of Vietnamese Coconut Varieties. Tạp chí Công nghệ Sinh học (Nhận đăng). Van PHP, Trang LDM, Nguyen NC, Thao NP, Hoang XLT* (2020) Transgenic Soybean Overexpressing GmNAC085 Enhanced Expression of Important Genes under Salinity Stress Condition. Tạp chí Công nghệ Sinh học 18(2):283-291. (*: tác giả liên hệ) Nguyen NC, Nguyen QT, Doan AT, Hoang XLT, Thao NP. (2019) Enhanced Tolerance to Abiotic Stresses in Transgenic Arabidopsis thaliana Plants Carrying GmNAC109 Gene. Tạp chí Công nghệ Sinh học 177(2):295-302. Thảo ĐTT, Hoàng XLT, Nguyễn BAT, Đoàn HN, Nguyễn VA, Thảo NP (2019) Tạo Cây Chuyển Gen Arabidopsis Biểu Hiện Vượt Mức GmHP08 Nhằm Phân Tích Vai Trò của GmHP08 Trong Cơ Chế Đáp Ứng với Stress Thẩm Thấu. Tạp chí Công nghệ Sinh học 17 (1): 87-95. Hoa TTK, Huỳnh NT, Thao NP, Hoang XLT* (2018) Drought Stress-Related Functional Characterization of Transcription Factor GmNAC085 in Soybean. Tạp chí Công nghệ Sinh học 16(4): 641-648. (*: tác giả liên hệ) Thái HV, Nguyễn NC, Hoang XLT, Thao NP (2018) Role of GmNAC019 Transcription Factor in Salinity and Drought Tolerance of Transgenic Arabidopsis thaliana. Tạp chí Công nghệ Sinh học 16(4): 611-619. Fulltext publications in Conference Proceedings Nhi NM, Tú NHC, Xuân HTL, Thảo NP (2019) Đánh Giá Khả Năng Chịu Hạn và Mặn của Cây Arabidopsis Có Biểu Hiện Vượt Mức Gen Đậu Tương GmRR34. Hội nghị Công nghệ Sinh học Toàn quốc (kỷ yếu). Nguyễn NC, Quang NT, Xuân HTL, Thảo NP (2019) Overexpression of GmNAC109 Alters Drought-Responsive Gene Expression in Arabidopsis thaliana under Water Deficit. Hội nghị Công nghệ Sinh học Toàn quốc (kỷ yếu).

[CV] Hoang Thi Lan Xuan, MSc. Read More »