Research Center for Infectious Diseases

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Huynh Chan Khon, PhD.

P.I.

Research Interest(s)

  • Bioactive Scaffold Design for Tissue Engineering,
  • Biomolecular Engineering,
  • Cell-Material Interaction,
  • Low cost microfluidic,
  • Point of care diagnostics.

Education

BS., Nong Lam University, HCMC

MS., Ajou University, Korea

Ph.D., University of Dusseldorf, Germany

Publications

  1. H.W. Lee, T.I. Kim, K.C.Huynh, M.H. Kwon, J.S. Kim, M. Jin, and Y.S. Kim, INDUCING RIGID LOCAL STRUCTURE AROUND THE ZINC-BINDING REGION BY HYDROPHOBIC INTERACTIONS ENHANCES THE HOMODIMERIZATION AND APOPTOTIC ACTIVITY OF ZINC-FREE TRAIL. Biochem Biophys Res Commun 62 (2007) 766-72.
  2. K.C. Huynh, V.R. Stoldt and R.E. Scharf, CONTRIBUTION OF DISTINCT PLATELET INTEGRINS TO BINDING, UNFOLDING AND ASSEMBLY OF FIBRONECTIN, Biological Chemistry, 2013, 394(11): 1485–1493
  3. H.T.Nguyen, K.C.Huynh, R.E.Scharf, and V.R.Stoldt, SHEAR-RELATED  FIBRILLOGENESIS  OF FIBRONECTIN, Biological Chemistry, 2013, 394(11): 1495–1503
  4. Assmann A, Delfs C, Munakata H, Schiffer F, Horstkötter K,  Huynh K, Barth M,Stoldt VR, Kamiya H, Boeken U, Lichtenberg A, Akhyari P., ACCELERATION OF AUTOLOGOUS IN VIVO RECELLULARIZATION OF DECELLULARIZED AORTIC CONDUITS BY FIBRONECTIN SURFACE COATING. Biomaterials. 2013 May, 34(25):6015-26
  5. K. Huynh, M. Gyenes, C. P. Hollenberg, TH. Nguyen, TV Vo, V. R. Stoldt, FIBRONECTIN UNFOLDED BY ADHERENT BUT NOT SUSPENDED PLATELETS: AN IN VITRO  EXPLANATION FOR ITS DUAL ROLE IN HAEMOSTASIS, Thrombosis Research 136 (2015) 803–812
  6. Khon C. Huynh, Thi-Hiep Nguyen, Dinh Chuong Pham, Huong T.T. Nguyen, Toi Van Vo, Marianna Gyenes and Volker R. Stoldt. INTEGRIN αIIbβ3-DEPENDENT ERK SIGNALING IS REGULATED BY Src KINASE AND Rho KINASE (ROCK) BOTH IN Leu33 AND Pro33 POLYMORPHIC ISOFORMS. Acta Haematologica, 2016, 137: 44-50
  7. Nguyen Thi Hiep, Huynh Chan Khon, VVT Niem, Vo Van Toi, TN Quyen, ND Hai, MNT Anh: Microwave-Assisted Synthesis of Chitosan/Polyvinyl Alcohol Silver Nanoparticles Gel for Wound Dressing Applications. International Journal of Polymer Science, 2016, Article ID 1584046
  8. Tra Thanh Nhi, Huynh Chan Khon, Nguyen Thi Thu Hoai, Bui Chi Bao,Tran Ngoc Quyen, Vo Van Toi, Nguyen Thi Hiep, FABRICATION OF ELECTROSPUN POLYCAPROLACTONE COATED WITHCHITOSAN-SILVER NANOPARTICLES MEMBRANES FOR WOUND DRESSING APPLICATIONS, J Mater Sci: Mater Med (2016) 27:156
  9. Nguyen Thi Hiep,  Huynh Chan Khon, Vo Van Thanh Niem, Vo Van Toi, Tran Ngoc Quyen, Nguyen Dai Hai,  and Mai Ngoc Tuan Anh, Microwave assisted synthesis of Chitosan/Polyvinyl alcohol silver nanoparticles gel for wound dressing applications, International Journal of Polymer Science, 2016, Article ID 1584046, 11 pages, Volume 2016
  10. Dang Hoang Phuc, Nguyen Thi Hiep, Do Ngoc Phuc Chau, Nguyen Thi Thu Hoai, Huynh Chan Khon, Vo Van Toi, Nguyen Dai Hai, and Bui Chi Bao, FABRICATION OF HYALURONAN-POLY(VINYLPHOSPHONIC ACID)-CHITOSAN HYDROGEL FOR WOUND HEALING APPLICATION, International Journal of Polymer Science, 2016, vol. 2016, Article ID 6723716, 9 pages
  11. Khon C. Huynh, Marianna Gyenes, Thi-Hiep Nguyen, Toi Van Vo and Volker R. Stoldt, IMPACT OF SHEAR STRESS ON SRC AND FAK PHOSPHORYLATION IN FIBRINOGEN-ADHERENT PLATELETS, Blood coagulation and fibrinolysis, June 2017, Volume 28, Issue 4, p 279-285.  
  12. Nguyen Thi Hiep, Huynh Chan Khon, Nguyen Dai Hai, Byong Taek Lee, Vo Van Toi and Le Thanh Hung. Fabrication of PCL/PLGA-BCP porous scaffold for bone tissue engineering applications. Journal of Biomaterials Science: Polymer Edition, 2017 
  13. Hiep Thi Nguyen, Hien Thu Luong, Khon Chan Huynh, Hai Dai Nguyen, Hien Anh Tran, and Toi Van Vo. Investigate the effect of thawing process on the self-assembly of silk protein for tissue application, BioMed Research International, 2017, Volume 2017, 1-16
  14. Alexander Assmann, Marc Struß, Franziska Schiffer, Friederike, Heidelberg, Hiroshi Munakata, Elena V. Timchenko, Pavel E. Timchenko, Tim Kaufmann, Khon Huynh, Yukiharu Sugimura, Quentin Leidl, Antonio Pinto, Volker R. Stoldt, Artur Lichtenberg, Payam Akhyari. IMPROVEMENT OF THE IN VIVO CELLULAR REPOPULATION OF DECELLULARIZED CARDIOVASCULAR TISSUES BY A DETERGENT-FREE, NON-PROTEOLYTIC, ACTIN DISASSEMBLING REGIMEN, Journal of Tissue Engineering and Regenerative Medicine, 2017, Volume 11, Issue 12 p. 3530-3543
  15. Nguyen Thi Hiep,Huynh Chan Khon,Nguyen Dai Hai,Lee Byong-Taek,Vo Van Toi & Le Thanh Hung, Biocompatibility of PCL/PLGA-BCP porous scaffold for bone tissue engineering applications, Journal of Biomaterials Science, 2017, 864-878
  16. Hiep Thi Nguyen, Hien Thu Luong, Hai Dai Nguyen, Hien Anh Tran, Khon Chan Huynh, and Toi Van Vo, Investigate the Effect of Thawing Process to the Self-assembly of Silk Protein for Tissue Applications, BioMed Research International, 2017, Article ID 4263762, 16 pages
  17. Khon C Huynh, Thi-Hiep Nguyen, Dinh Chuong Pham, Huong T T Nguyen, Toi Van Vo, Marianna Gyenes, Volker R Stoldt, Integrin αIIbβ3-dependent Erk signaling is regulated by Src kinase and Rho kinase both in Leu33 and Pro33 polymorphic isoforms, Acta Haematologica, 2017, 137: 44-50
  18. Hien Thi-Thu Pham, Anh Le-Trang Nguyen, Toi-Van Vo, Khon-Chan Huynh, and Quoc-Hung Phan, Optical parameters of human blood plasma, collagen, and calfskin based on the Stokes–Mueller technique, Applied Optics, 2018, 4353-4359
  19. Luong Thu Hien, Nguyen Thanh Truc, Vo Van Toi, Huynh Chan Khon, Bui Chi Bao, Vo Van Thanh Niem, Mai Ngoc Tuan Anh, Nguyen Dai Hai, Pham Dinh Chuong, and Nguyen Thi Hiep, Evaluation of the morphology and biocompatibility of natural Silk Fibers/Agar Blend scaffolds for tissue regeneration, International Journal of Polymer Science, 2018, Article ID 5049728, 7 pages
  20. Hoang-Tuan Nguyen, Ha Thach, Emmanuel Roy, Khon Huynh*, Cecile Mong-Tu Perraul*, LOW-COST, ACCESSIBLE FABRICATION METHODS FOR MICROFLUIDICS RESEARCH IN LOW-RESOURCE SETTINGS. Micromachines, 2018, 9(9), 461
  21. Khon Huynh, Thi-Hiep Nguyen, Phuong Thao Nguyen Thi, Ngoc Quyen Tran, Van Toi Vo, Marianna Gyenes, and Volker R. Stoldt, LEU33PRO (PLA) POLYMORPHISM OF INTEGRIN BETA3 MODULATES PLATELET SRC PY418 AND FAK PY397 PHOSPHORYLATION IN RESPONSE TO ABNORMALLY HIGH SHEAR STRESS. Blood Coagulation and Fibrinolysis, 2018, Volume 29 – Issue 6 – p 488-495
  22. Phung Ngan Le, Chan Khon Huynh, Ngoc Quyen Tran. Advances in thermosensitive polymer-grafted platforms for biomedical applications. Material Science and Engineering C, 1 November 2018,  Vol 92, pp 1016-1030.
  23. Huong Nguyen, Khon Huynh and Volker R Stoldt. Shear-dependent fibrillogenesis of fibronectin: impact of platelet integrins and actin cytoskeleton. Biochemical and Biophysical Research Communications, 4 March 2018 Vol 497, Issue 2, pp 797-803
  24. Tien Thinh Nguyen, Chan Khon Huynh, Van Thu Le , Minh Dung Truong, Bach Long Giang, Ngoc Quyen Tran & Minh Thanh Vu. In situ Fabrication of Biological Chitosan and Gelatin-Based Hydrogels Loading Biphasic Calcium Phosphate Nanoparticles for Bone Tissue Regeneration, Asian journal of chemistry, 2019, 31, 5, 1062-1070
  25. Huy Quang Do, Trinh Van Le, Minh Thanh Dang, Tien-Trieu Pham-Le, Luan Van Tran, Khon Chan Huynh, Ai-Xuan Le Holterman, Nhung Hai Truong, Recombinant human granulocyte colony-stimulating factor alleviates liver fibrosis in bile duct-ligated mice, Biomedical Research and Therapy, 2019, 6(6):3222-3232
  26. Phuong-Thao Nguyen-Thi, Quoc Phong Le, Volker R. Stoldt, Ngoc Quyen Tran, Anh Tho Le, Khon Huynh, Morphologies of Fibronectin Fibrils Formed under Shear Conditions and Their Cellular adhesiveness Properties, Molecular & Cellular Biomechanics, 2020, online first, Forsyth Vol. 17, Iss. 3
  27. Thien Hoang, Bao-Han Ly, Thanh-Xuan Le, Thanh-Thao Huynh, Hoang-Tuan Nguyen, Toi Van Vo, Thi Thu Hien Pham, Khon Huynh, Minimal microfabrication required digital microfluidic system toward point-of-care nucleic acid amplification test application for developing countries, Microsystem Technologies, 2020, 26, 1863-1873
  28. Phong Le, Hoang-Nghi Mai-Thi, Volker R. Stoldt, Ngoc Quyen Tran and Khon Huynh, Morphological dependent effect of cell-free formed supramolecular fibronectin on cellular activities, Biological chemistry, 2020, 19;402(2):155-165

Awards

  1. Abstract Achievement Award – ISTH 2011 Congress, Tokyo, Japan
  2. Travel Award – ISTH 2015 Congress, Toronto, Canada
  3. Travel Award – ISTH 2017 Congress, Berlin, Germany
  4. Bằng khen Giảng viên Hướng dẫn Sinh viên đạt giải Nhất cuộc thi “Sinh viên nghiên cứu khoa học” (Đề tài “Tổng hợp sợi Fibronectin trong điều kiện không tế bào: Nghiên cứu sự ảnh hưởng của hình thái sợi Fibronectin lên hoạt tính sinh học và chức năng của tiểu cầu” sinh viên Lê Quốc Phong –  Trường Đại học Quốc tế, Đại học Quốc gia TP.HCM.)
  5. Giấy khen Giảng viên có thành tích công bố khoa học công nghệ xuất sắc
  6. ISTH Fellowships – ISTH Education Committee, Berlin, Germany
  7. Travel Award – GTH 2019 Dusseldorf, Germany
  8. Bằng khen tặng giải Nhì Hội thi Sáng tạo Kỹ thuật Thành phố Hồ Chí Minh năm 2017-2018